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List of Publications: Professor Tasuku Honjo Awarded the Nobel Prize

 On 2018-12-11 (18908 reads)

The 2018 Nobel Prize in Physiology or Medicine has been awarded in part to Tasuku Honjo, distinguished professor and deputy director-general at the Kyoto University Institute for Advanced Study (KUIAS).

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■ The Selected List of Publications of Professor Tasuku Honjo

Reference: CV & Selected Publications (Department of Immunology and Genomic Medicine, Kyoto University Graduate School of Medicine)

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◆Studies on Immuno-inhibotory receptor PD-1

  • Induced expression of PD‐1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.
    Y. Ishida, Y. Agata, K. Shibahara, T. Honjo.
    EMBO J. 11 3887-3895 (1992).
    DOI: 10.1002/j.1460-2075.1992.tb05481.x
  • Development of Lupus-like Autoimmune Diseases by Disruption of the PD-1 Gene Encoding an ITIM Motif-Carrying Immunoreceptor.
    Nishimura, H., Nose, M., Hiai, H., Minato, N. and Honjo, T.
    Immunity 11 141-151 (1999).
    DOI: 10.1016/S1074-7613(00)80089-8
  • Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation.
    Freeman, G. J., Long, A. J., Iwai, Y., Bourque, K., Chernova, T., Nishimura, H., Fitsz, L. J., Malenkovich, N., Okazaki, T., Byrne, M. C., Horton, H. F., Fouser, L., Carter, L., Ling, V., Bowman, M. R., Carreno, B. M., Collins, M., Wood, C. R. and Honjo, T.
    J. Exp. Med. 192 1027-1034 (2000).
    DOI: 10.1084/jem.192.7.1027
  • PD-L2 is a second ligand for PD-1 and inhibits T cell activation.
    Latchman, Y., Wood, C., Chernova, T., Borde, M., Chernova, I., Iwai, Y., Malenkovich, N., Long, A., Bourque, K., Boussiotis, V., Nishimura, H., Honjo, T., Sharpe, A. and Freeman, G.
    Nature Immunol. 2 261-268 (2001)
    DOI: 10.1038/85330
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  • Autoimmune dilated cardiomyopathy in PD-1 receptor deficient mice.
    Nishimura, H., Tanaka, Y., Okazaki, T., Nakatani, K., Hara, M., Matsumori, A., Sasayama, S., Hiai, H., Minato, N. and Honjo, T.
    Science 291 319-322 (2001)
    DOI: 10.1126/science.291.5502.319
  • Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade.
    Iwai, Y., shida, M., Tanaka, Y., Okazaki, T., Honjo, T. and Minato, N.
    Proc. Natl. Acad. Sci. USA 99 12293-12297 (2002)
    DOI: 10.1073/pnas.192461099
  • Autoantibodies against cardiac troponin I are responsible for the dilated cardiomyopathy in PD-1 deficient mice.
    Okazaki, T., Tanaka, Y., Nishio, R., Mitsuie, T., Mizoguchi, A., Jian, W., Ishida, M., Matsumori, A., Minato,. N. and Honjo, T.
    Nature Medicine 9 1477-1483 (2003)
    DOI: 10.1038/nm955
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  • Rejuvenating exhausted T cells during chronic viral infection.
    Okazaki T, Honjo T.
    Cell. 124(3):459-61 (2006)
    DOI: 10.1016/j.cell.2006.01.022
  • Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer.
    Hamanishi J, Mandai M, Iwasaki M, Okazaki T, Tanaka Y, Yamaguchi K, Higuchi T, Yagi H, Takakura K, Minato N, Honjo T, Fujii S.
    PNAS. 104(9):3360-5 (2007)
    DOI: 10.1073/pnas.0611533104
  • TRIM28 prevents autoinflammatory T cell development in vivo.
    Chikuma S, Suita N, Okazaki IM, Shibayama S, Honjo T.
    Nat Immunol. 13(6):596-603 (2012)
    DOI: 10.1038/ni.2293
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  • A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application.
    Okazaki T, Chikuma S, Iwai Y, Fagarasan S, Honjo T.
    Nat Immunol. 14(12):1212-8 Review (2013)
    DOI: 10.1038/ni.2762
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◆Doctoral Dissertation


    Honjo, Tasuku (本庶, 佑) 
    Kyoto University,  Ph.D. in Medical Science, 医博第463号
    Date Granted: January 23, 1975
    Abstract: KURENAI:

◆Articles in Kyoto University Research Information Repository KURENAI (other than that above)

◆Articles in Japanese

本庶佑京都大学名誉教授の医中誌収録文献  (Japan Medical Abstracts Society (JAMAS))   

 (Academic Support Section, Kyoto University Library)